After graduating from the Free University Amsterdam as a biologist, Jan Vermeiden participated in the research project with prof. Dr. Zeilmaker in Rotterdam, which led to a PhD degree in 1974. The research project resulted in the first IVF success in 1983 in the Netherlands. After that he was working as a teacher embryology at the Free University. In 1984 he was the initiator of the IVF clinic at the VUMC. Between 1984 and 2002 he managed the IVF laboratory. Nowadays he is still involved in research lines to improve the results in reproductive medicines.